Mitochondrial-derived 16-amino-acid peptide
Encoded within the mitochondrial 12S rRNA region and used to study communication between mitochondria and the nucleus.
Available
LONGEVITY / RESEARCH COMPOUND
MOTS-c
External Community Polls · Not Product ReviewsAvailable Sizes3 sizes
CategoryLongevity
Price · 10 mg₹4,600
Request Batch Documents Batch documentation is shared privately on request; availability is lot-specific.
Multi-Vial Savings
5+ vials: 10% off
Cash on DeliveryEligible PIN CodesIndia-wide deliveryPurity guaranteeMoney back if purity is below 99%
About the Batch Report
Analytical results apply to a specific sample, batch and test method. Ask about the exact lot being offered; do not assume a generic purity figure or test panel applies to every batch.
Understand Batch Test Reports ↗Available
For laboratory research use only. Not for human consumption. No treatment or self-administration guidance is provided.
About MOTS-c
MOTS-c is a mitochondrial-derived 16-amino-acid peptide studied as a metabolic stress signal, particularly through AMPK, glucose handling and exercise-response models.
AMPK-linked metabolic and stress-response signalling
A mitochondrial-derived peptide studied in cellular-stress and metabolic research models.
MOTS-c · Research Mechanism
Explore receptor targets and downstream signalling studied for this compound.
Folate–purine metabolism
Alters folate-linked purine synthesis and AICAR accumulation.
View primary studyAMPK activation
Engages the cellular energy-sensing pathway.
View primary studyMOTSC
RESEARCH
PROFILE
RESEARCH
PROFILE
Nuclear stress signalling
Moves into the nucleus during metabolic stress.
View primary studyInsulin-responsive glucose handling
Influences skeletal-muscle glucose metabolism in experimental models.
View primary studyThe cited study model identifies where each pathway was observed.
Published Research & Findings
Expand each group. Categories follow the linked Pep-Pedia source profile. Labels describe relative research emphasis and are not clinical efficacy grades.
MetabolicMost effective＋
Insulin Resistance
Improves insulin sensitivity by ~30% in animal studies through AMPK activation. Enhances glucose uptake in skeletal muscle and improves glucose tolerance.
Type 2 Diabetes
Clinical trials show improved glucose homeostasis. Restores metabolic function through enhanced insulin receptor sensitization and AMPK-mediated metabolic regulation.
Obesity Prevention
Prevents obesity despite identical caloric intake in animal models. Promotes fatty acid oxidation and thermogenesis through mitochondrial activation.
Anti AgingEffective＋
Physical Performance
Reverses age-dependent physical decline in animal studies. Improved grip strength, gait parameters, and exercise capacity in aged mice.
Mitochondrial Function
Enhances mitochondrial biogenesis through PGC-1α activation. Improves mitochondrial respiratory capacity and energy production.
Longevity
Late-life treatment showed 6.4% median lifespan extension in mice. Age-related decline of 21% in elderly humans suggests therapeutic potential.
ExerciseModerate＋
Exercise Capacity
Single dose improved running time by 12% and distance by 15% in mice. Exercise induces 11.9-fold increase in skeletal muscle MOTS-c.
Muscle Homeostasis
Supports muscle health through myostatin reduction and anti-atrophy effects. Positively correlated with muscle strength and power in humans.
Recovery
Promotes mitochondrial biogenesis and reduces inflammatory markers. Enhances metabolic flexibility for improved recovery.
Public Community Polls & Research Discussions
Pep-Pedia community poll distributions. Every response option returned for each displayed question is shown.
Primary goal
Fat loss31%
General wellness30%
Anti-aging14%
Muscle growth8%
Recovery/Healing4%
Show all 28 answer optionsShow top 5＋
Cognitive enhancement4%
Other: Energy2%
Other (please specify)1%
Other: Energy 1%
Other: Insulin Sensitivity 0%
Other: Energy and Endurance0%
Other: All of the above0%
Other: Moto health0%
Other: Higher Endurance 0%
Other: Energy/stamina0%
Other: Mitochondrial health0%
Other: Mitochondrial benefits0%
Other: Exercise enhancement 0%
Other: Combination of anti-aging, improve energy, fat loss, and muscle growth0%
Other: Energy, wellness0%
Other: Improved energy and metabolism 0%
Other: Enhanced workouts helps with loss of energy when taking Reta0%
Other: Fatigue from past psych med use0%
Other: Endurance 0%
Other: Energy and fat loss 0%
Other: Stamina0%
Other: Diabetes0%
Other: Energy while exercising 0%
Effectiveness
Too early to tell39%
Somewhat effective20%
Very effective18%
Neutral12%
Not very effective2%
Show all 31 answer optionsShow top 5＋
Other (please specify)2%
Not effective at all1%
Other: Haven’t started 1%
Other: Haven’t started yet0%
Other: Haven't started using it 0%
Other: Haven’t started taking it0%
Other: I took it for 1 month and didn’t notice any significant changes. I’m about to start it again and will try a slightly higher dose. 0%
Other: haven't started yet0%
Other: Had an anaphylactic reaction to it0%
Other: Not started yet 0%
Other: Have not tried yet0%
Other: Not started 0%
Other: Haven’t used0%
Other: Not started yet0%
Other: AUN NO LO USO 0%
Other: N/A0%
Other: Not using it ye0%
Other: NA0%
Other: Not started0%
Other: Have not started0%
Other: N/A haven't used yet0%
Other: Haven’t started yet 0%
Other: Felt effective in giving energy and performance, however felt a lot of sides 0%
Other: About to start today0%
Other: Haven't started. Just researching0%
Other: I haven't started taking it yet 0%
Side effects
No side effects44%
Injection site reaction25%
Fatigue7%
Other (please specify)5%
Headache4%
Show all 33 answer optionsShow top 5＋
Insomnia3%
Dizziness3%
Nausea1%
Other: N/A1%
Water retention0%
Other: Haven't used it0%
Other: Haven’t started taking it0%
Other: just starting0%
Other: Not start yet0%
Other: Not started yet0%
Other: haven't started yet0%
Other: Haven’t started 0%
Other: Flushing, dizziness,neck swelling 0%
Other: Not started 0%
Other: Brain fog 0%
Other: AUN NO LO USO 0%
Other: Slight heart palpitations 0%
Other: Haven’t started it yet0%
Other: have not started yet0%
Other: Haven’t tried yet0%
Other: ainda não apliquei0%
Joint pain0%
Other: Diarrhea 0%
Other: Not using yet0%
Other: Na0%
Other: Significant blood pressure drop0%
Other: Too early to tell0%
Other: Have not started0%
Would recommend
Definitely yes35%
Probably yes30%
Not sure28%
Other (please specify)2%
Probably not1%
Show all 19 answer optionsShow top 5＋
Definitely not1%
Other: Not applicable 1%
Other: Just research 0%
Other: Haven’t started taking it0%
Other: To early to Tell0%
Other: haven't started yet0%
Other: Once tried 0%
Other: NO LO USO 0%
Other: Unsure yet0%
Other: não apliquei ainda0%
Other: Na0%
Other: Have not used yet0%
Other: N/A0%
Other: Haven't started taking it yet Haven't started taking it yet0%
Anonymous self-reporting is subject to selection bias and is not clinical evidence. Percentages describe community responses and may not total exactly 100% because of rounding. Snapshot captured 2026-10-16; the source refreshes in the background.
Reported Study Observations & Adverse Events
Research context belongs beside—not above—the safety and evidence boundary.
* Source context: Pep-Pedia research profile ↗. This catalogue uses a research-only summary and does not reproduce protocol or self-use instructions.
Reported observation window*
STAGE 1
Weeks 1–2 · AMPK activity and early glucose-tolerance changes are the main research focus
STAGE 2
Weeks 2–4 · exercise capacity and insulin-sensitivity measures may change
STAGE 3
Weeks 4–8 · studies assess whether metabolic and body-composition effects continue
STAGE 4
Weeks 8–12 · mitochondrial function and metabolic flexibility are evaluated over the longer observation window
Published Evidence & Trial Context
Study type is part of the product information. Laboratory, animal, observational and controlled human findings are not interchangeable.
METABOLIC
Improves insulin sensitivity by ~30% in animal studies through AMPK activation. Enhances glucose uptake in skeletal muscle and improves glucose tolerance.
ANTI AGING
Reverses age-dependent physical decline in animal studies. Improved grip strength, gait parameters, and exercise capacity in aged mice.
EXERCISE
Single dose improved running time by 12% and distance by 15% in mice. Exercise induces 11.9-fold increase in skeletal muscle MOTS-c.
References & citations.＋
Selected studies and source context.
Curated starting points, not a systematic review, comparative ranking or batch-test record. Follow the source for the full methods and results.
| Source | Study model | Measured topic and limitations |
|---|---|---|
| MOTS-c metabolic signalling study ↗Lee et al. · 2015 · PMID 25738459 | Cellular experiments and mouse models | Examines AMPK-linked signalling and metabolic homeostasis. The discovery study is not a controlled human outcome study or a test of our catalogue batch. |
MOTS-c identity and research evidence · Batch COA checklist · Presentation and blend labels · Publisher and source policy
01MOTS-c research profileContent-synthesis source for indications, timelines, safety context and community reportingView source ↗
03ClinicalTrials.gov records for MOTS-cSearch registered studies and their current statusView source ↗
Frequently Asked Questions
What is the MOTS-c price in India?＋
The currently listed INR prices are 10 mg: ₹4,600; 20 mg: ₹7,000; 40 mg: ₹10,000. The prices above are for the labelled research presentations. Confirm availability, delivery charges and the final order total before payment.
Do MOTS-c, MOTS-C and MOTS C identify different products?＋
These capitalisation and spacing variants refer to the same peptide name. The comparison still needs the full material identity, labelled milligrams and batch documentation. A research paper about MOTS-c does not verify the contents or quality of a particular catalogue vial.
What other names are used for MOTS-c?＋
MOTS C; mitochondrial-derived MOTS-c peptide are names used in material searches. A mitochondrial-derived peptide studied in metabolic and cellular-stress models. Match the full label, form and batch documents; an alias alone does not authenticate a product.
How does MOTS-c compare with SS-31?＋
A mitochondrial-derived peptide studied in metabolic and cellular-stress models. A mitochondria-targeted research peptide. Match the exact material and study formulation when reading elamipretide literature. Compare identity, component amounts and the actual study model. Shared research topics do not establish equivalent effects.
Can MOTS-c be delivered to Mumbai, Delhi, Bengaluru, Hyderabad, Chennai or Pune?＋
Delivery enquiries are welcome for these cities and other Indian destinations, subject to the actual PIN code. Standard delivery: ₹150, estimated 3–5 days. Express delivery: ₹350, estimated 2–3 days. Cash on delivery adds ₹150. Confirm PIN-code serviceability and the delivery estimate before ordering.
When can I request a return or refund for MOTS-c?＋
Returns and refunds are available for products damaged on arrival or if purity is below 99%. Retain the order reference, packaging and relevant batch records; contact the team to confirm the claim process.
How do I order MOTS-c for research in India?＋
Select the labelled presentation and quantity, review the cart, then send the order enquiry on WhatsApp. Share your Indian PIN code so the team can confirm stock, serviceability, delivery charges and the final INR total before payment. The listed material is for laboratory research only, not for human consumption.
How can I check the MOTS-c batch COA and India delivery?＋
Use the batch COA request link on this page and specify the selected presentation. Ask the team to match available documentation to the current batch and confirm delivery to your Indian PIN code before payment. Compare the report identity, test method and measured result with the material offered.
How much is shipping for MOTS-c in India, and is cash on delivery available?＋
Standard delivery across India costs ₹150 and usually takes 3–5 days. Express delivery costs ₹350 and usually takes 2–3 days. Cash on delivery is available for an extra ₹150. The team confirms serviceability for your PIN code and the final total on WhatsApp before dispatch.
Can I buy MOTS-c in Mumbai, Delhi, Bangalore or Hyderabad?＋
Yes. The Peptide Co. ships from Bengaluru to eligible PIN codes across India, including Mumbai, Delhi NCR, Bengaluru (Bangalore), Hyderabad, Chennai, Pune, Kolkata and Ahmedabad. Share your PIN code on WhatsApp to confirm serviceability and the delivery estimate for your address.
What other names is MOTS-c known by?＋
MOTS-c is also known as MOTS C, mitochondrial-derived MOTS-c peptide. These names describe the same listing on this page; always match the labelled identity and batch documentation rather than relying on a name alone.
Is the MOTS-c listing price on this page current?＋
As of 1 November 2026, this page shows 3 listed presentations for MOTS-c, and prices on the page are read from the live catalogue each time it loads. Current availability is shown with the listed sizes. Your final total is confirmed on WhatsApp.
What exactly is MOTS-c?＋
MOTS-c is classified as mitochondrial-derived 16-amino-acid peptide. Encoded within the mitochondrial 12S rRNA region and used to study communication between mitochondria and the nucleus.
What is MOTS-c studied for?＋
Its principal research areas are mitochondrial signalling, metabolic homeostasis, stress-response pathways. These describe experimental topics, not guaranteed outcomes or approved indications.
What form does the product arrive in?＋
10 mg · 20 mg · 40 mg lyophilized research material in a sealed glass vial. Appearance: White to off-white lyophilized powder. Always compare the received vial with its lot-specific documentation.
How should the unopened material be stored?＋
Keep sealed, dry and protected from light/moisture. Store at 2–8°C short-term and ≤−20°C long-term unless the batch documentation states otherwise.
Is MOTS-c approved for human use?＋
Investigational. This catalogue presentation is restricted to laboratory research material and does not provide dosing, treatment or self-administration guidance.