Synthetic tri-receptor agonist peptide
A 39-amino-acid investigational peptide with a lipid modification studied for prolonged receptor exposure.
Available
METABOLIC / RESEARCH COMPOUND
Retatrutide
External Community Polls · Not Product ReviewsAvailable Sizes5 sizes
CategoryMetabolic
Price · 10 mg₹5,500
Request Batch Documents Batch documentation is shared privately on request; availability is lot-specific.
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5+ vials: 10% off
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About the Batch Report
Analytical results apply to a specific sample, batch and test method. Ask about the exact lot being offered; do not assume a generic purity figure or test panel applies to every batch.
Understand Batch Test Reports ↗Available
For laboratory research use only. Not for human consumption. No treatment or self-administration guidance is provided.
About Retatrutide
A 39-amino-acid investigational peptide studied as a triple GLP-1, GIP and glucagon receptor agonist. Pep-Pedia centres its profile on weight, glycaemic and cardiovascular research while noting that development and safety evaluation remain ongoing.
GLP-1R, GIPR and glucagon-receptor signalling
An investigational triple-receptor peptide, with listed research presentations, prices and compound specifications.
Retatrutide · Research Mechanism
Explore receptor targets and downstream signalling studied for this compound.
GLP-1 receptor activation
Activates an incretin receptor involved in glucose and appetite signalling.
View primary studyGIP receptor activation
Engages the second incretin pathway through GIPR.
View primary studyRETA
RESEARCH
PROFILE
RESEARCH
PROFILE
Glucagon receptor activation
Adds glucagon signalling to the two incretin pathways.
View primary studyGs–cAMP signalling
All three receptors connect to intracellular second-messenger signalling.
View primary studyThe cited study model identifies where each pathway was observed.
Published Research & Findings
Expand each group. Categories follow the linked Pep-Pedia source profile. Labels describe relative research emphasis and are not clinical efficacy grades.
Weight LossMost effective＋
Superior Weight Reduction
Clinical trials demonstrate 17.5% at 24 weeks and 24.2% at 48 weeks - highest recorded for any obesity medication in development
Sustained Weight Management
Continuous weight loss throughout trials with no plateau reached at 48 weeks, suggesting greater long-term potential than current therapies
Triple Mechanism Obesity Treatment
Addresses obesity through appetite suppression, increased energy expenditure, and improved metabolic efficiency via three hormone pathways
DiabetesEffective＋
Superior Glycemic Control
HbA1c reductions up to 2.16% with 82% of participants achieving target levels below 6.5% - exceeding dual agonist performance
Glucose-Dependent Regulation
Glucose-dependent insulin secretion and glucagon suppression provide balanced glycemic control with minimal hypoglycemia risk
Insulin Sensitivity Enhancement
Marked improvements in insulin sensitivity with potential for significant reduction in exogenous insulin requirements
CardiovascularModerate＋
Comprehensive Lipid Improvement
Non-HDL cholesterol reductions up to 26.9%, triglyceride reductions up to 40.6%, and ApoB reductions up to 24.2%
Blood Pressure Optimization
Consistent decreases in both systolic and diastolic blood pressure across clinical trials, supporting cardiovascular risk reduction
Hepatic Fat Reduction
Up to 82% reduction in liver fat with normalization in 90% of participants, addressing MASLD and reducing cardiovascular risk
Public Community Polls & Research Discussions
Pep-Pedia community poll distributions. Every response option returned for each displayed question is shown.
Primary goal
Fat loss90%
General wellness6%
Muscle growth2%
Anti-aging0%
Recovery/Healing0%
Show all 31 answer optionsShow top 5＋
Cognitive enhancement0%
Other (please specify)0%
Other: fat loss and muscle growth and insuling sensitivity0%
Other: Weight loss and general wellness0%
Other: Muscle growth and fat loss0%
Other: Reduce inflammation 0%
Other: Oxidation of fat accumulation in my liver0%
Other: Autoimmune reduction and weight loss0%
Other: Weight loss at first now general wellness0%
Other: Maintenance. Not to gain weight.0%
Other: To totally get off all other diabetic medication 0%
Other: Type 2 diabetic 0%
Other: B0%
Other: Better metabolism and energy levels0%
Other: blood sugar0%
Other: Type 2 diabetes 0%
Other: Weight loss0%
Other: Hormonal balance 0%
Other: Hba1c 0%
Other: Cardiology 0%
Other: Insulin Resistance control0%
Other: T2DM0%
Other: weight maintenance 0%
Other: Weight maintenance 0%
Other: Weight loss 0%
Other: PCOS management0%
Effectiveness
Very effective41%
Too early to tell26%
Somewhat effective19%
Neutral4%
Other (please specify)2%
Show all 67 answer optionsShow top 5＋
Not very effective2%
Not effective at all1%
Other: Haven’t started yet 0%
Other: Have not started 0%
Other: Haven’t started 0%
Other: N/A0%
Other: Not using0%
Other: Haven't started yet0%
Other: Haven’t started yet0%
Other: Haven’t started0%
Other: Na0%
Other: havent started0%
Other: Haven't started 0%
Other: n/a0%
Other: Not taking yet0%
Other: Not started0%
Other: Not started yet0%
Other: I have not started 0%
Other: Can’t find source0%
Other: not started yet0%
Other: Researching0%
Other: Never used it. I’m just researching.0%
Other: Never used it just do research0%
Other: Not used yet 0%
Other: Just started today. 0%
Other: Haven’t used it0%
Other: not yet started0%
Other: i haven’t started yet0%
Other: N/a0%
Other: Not started yet. On Semaglutide. 0%
Other: Have not started0%
Other: Não uso 0%
Other: Not on it yet0%
Other: First time customer0%
Other: Not on it0%
Other: NA 0%
Other: Haven’t used0%
Other: Not using yet0%
Other: Haven’t started using it yet 0%
Other: Havent started0%
Other: I’ve just moved up to 1 mg so it’s too early to tell0%
Other: Have not used 0%
Other: Haven’t started it0%
Other: Didn’t use0%
Other: Not applicable0%
Other: Haven't started0%
Other: Just learning about it now0%
Other: haven't started 0%
Other: never used it0%
Other: Im doing 1 ml a week got severe abdominal pain throwing up and diarrhea 0%
Other: Have not started yet0%
Other: Have not use it0%
Other: Ive never tried 0%
Other: Havent started taking yet0%
Other: Not taking 0%
Other: Haven’t tried this peptide 0%
Other: It using0%
Other: je n'est pas encore commencé à utiliser0%
Other: Not started 0%
Other: Not yet started0%
Other: Only 6weeks on have lost a good amount of weight 0%
Other: Not using 0%
Side effects
No side effects24%
Nausea18%
Fatigue15%
Headache10%
Other (please specify)5%
Show all 155 answer optionsShow top 5＋
Insomnia5%
Dizziness4%
Injection site reaction3%
Joint pain3%
Water retention2%
Other: Constipation1%
Other: Diarrhea 0%
Other: Skin sensitivity 0%
Other: N/A0%
Other: Diarrhea0%
Other: Haven’t started 0%
Other: Skin sensitivity0%
Other: Constipation 0%
Other: Allodynia0%
Other: Diarrhoea 0%
Other: constipation0%
Other: Na0%
Other: diarrhea0%
Other: NA0%
Other: Increased heart rate 0%
Other: acid reflux0%
Other: Haven’t started yet 0%
Other: Haven't started yet0%
Other: Hair loss0%
Other: havent started0%
Other: Dehydration0%
Other: Not started yet0%
Other: Haven’t started yet0%
Other: n/a0%
Other: N/a0%
Other: heartburn0%
Other: Have not started 0%
Other: lower bowel movements0%
Other: Skin pain/sensitivity0%
Other: Constipation after first increase but that went away0%
Other: Anhedonia0%
Other: Intense diarrhea0%
Other: Bilateral lower back pain0%
Other: Skin pain0%
Other: Stiff neck0%
Other: Generalized itching 0%
Other: No use yet0%
Other: Skin sensitivity, one Spot at my back that hurted like hell white touching @ 5mg0%
Other: dehydration0%
Other: Can’t find source0%
Other: Not started0%
Other: Sensitive skin0%
Other: Dysesthesia0%
Other: Erratic Blood pressure 0%
Other: Too much weight loss0%
Other: Not applicable 0%
Other: Researching0%
Other: Never used it0%
Other: Skin Sensitivity0%
Other: Heartburn 0%
Other: Increased Heart Rate0%
Other: RHR Increase 0%
Other: Burping0%
Other: Body Tenderness0%
Other: Heart palpitations 0%
Other: Increased HR0%
Other: Resting heart rate0%
Other: Haven’t used 0%
Other: diarrhea, heartburn, bloating0%
Other: Full body sensitivity similar to flu0%
Other: Palpitations 0%
Other: Cold hands and feet0%
Other: Dysesthesia 0%
Other: Burn, itchy skin, rashes. 0%
Other: Not started yet.0%
Other: Skin sensitivity to the touch - specifically inner arms; and I’m always freezing -easily cold 0%
Other: Reflux early on when titrating too fast. Backed off dosage, and titrated up slowly from there, reflux resolved. 0%
Other: Skin sensitivity and muscle aches 0%
Other: Libido0%
Other: thirsty, skin sensitive, diarrhea0%
Other: Haven't started 0%
Other: Haven’t started using yet0%
Other: Not used0%
Other: Not start yet0%
Other: Full body skin sensitivity 0%
Other: no energy started in week 4, anhedoni started in week 5 and had to stop it, sometimes diharee0%
Other: Elevated heart rate but worth mentioning I have high level of acidity and reflux that sometimes affects my heart rythm0%
Other: Constipation and Insomnia 0%
Other: Reflux 0%
Other: Not on it yet0%
Other: High heart rate0%
Other: Too early 0%
Other: anhedonia 0%
Other: thirsty 0%
Other: skin sensitivty0%
Other: skin sensitivity0%
Other: constipation 0%
Other: Diarrea 0%
Other: Weakness in high cardio volume. 0%
Other: Insomnia, but it after 8wks it resolved0%
Other: Sulfur burps0%
Other: Constipation/diarrhea0%
Other: Skin sensitivity, muscle pain, constipation 0%
Other: Just started ten minutes ago0%
Other: Delayed gastric emptying0%
Other: Diarrhea, constipation0%
Other: Reduced LiBido0%
Other: Occasionally diarrhea during a dose increase0%
Other: Sensitive skin 0%
Other: Feeling full after a few bites of food and heartburn medications stop working. 0%
Other: GI effects0%
Other: easily cold0%
Other: Started low, at .5mg. No side effects but it’s working. 0%
Other: Slow Bowel movement 0%
Other: Skin sensitivity, decreasing after several weeks0%
Other: Dizziness 0%
Other: Soft Stools0%
Other: Poor sleep in early stages0%
Other: Both constipation and diarrhea0%
Other: Allydonia 0%
Other: Heart palpitations0%
Other: Weird dull pain in side close to gallbladder or coming from gall bladder0%
Other: muscle soreness 0%
Other: Haven't used it0%
Other: Flu like symptoms 0%
Other: Diarrhea abdominal pain0%
Other: Faster heart palpitations0%
Other: Heartburn0%
Other: Itchy skin0%
Other: Thirsty0%
Other: Pins and needles for about 1-2 weeks after escalating dose to 3mg0%
Other: Extreme fatigue 0%
Other: diaree 0%
Other: Menstrual cycle affected by prolonged bleeding (30 days)0%
Other: Anxiety 0%
Other: Sometimes diarrhea. Sometimes constipation. Gassy 0%
Other: High heart rate 0%
Other: Sensitive skin sensations, reduced over time. 0%
Other: Easily gotten cold0%
Other: Diarrhoea and constipation 0%
Other: Didn't start0%
Other: Depression 0%
Other: Gassy belly. sulfur burps are starting after 3 weeks of upping dose to 4 mg. 0%
Other: Mild constipation0%
Other: diarrhea 0%
Other: non0%
Other: Constipatio 0%
Other: Slowing of gastric emptying0%
Other: Constipation,vlikely due to dehydration 0%
Other: Skin sensitivity and aches 0%
Other: Haven’t started0%
Other: Have not started0%
Other: Lack of bowel movements. 0%
Other: Does not apply I haven’t started meds yet0%
Other: Haven’t started the Reta yet just researching 0%
Would recommend
Definitely yes59%
Probably yes21%
Not sure14%
Other (please specify)2%
Probably not0%
Show all 38 answer optionsShow top 5＋
Other: Haven’t started 0%
Other: N/A0%
Definitely not0%
Other: Haven't started yet0%
Other: Na0%
Other: Too early to tell0%
Other: Unknown yet 0%
Other: Shanxi Qianyecao Biotech QYC0%
Other: To early to tell 0%
Other: hacebt started0%
Other: Have not Started 0%
Other: Me experience with it0%
Other: Not sure yet 0%
Other: Never used it just researching 0%
Other: Will let you know.0%
Other: n/a0%
Other: i haven’t taken it0%
Other: Maybe0%
Other: Yes, 100% with all of the data you guys have been collecting over the Years I feel very comfortable in your product and I can’t wait to try it0%
Other: Under guidance from MD 0%
Other: Too early to day0%
Other: Not using it yet 0%
Other: I have not used it yet0%
Other: Haven’t used yet0%
Other: Have not stated 0%
Other: Not applicable0%
Other: na0%
Other: Too early yet as i’m on week 1 0%
Other: Didn't start0%
Other: havent started0%
Other: Not started0%
Other: Too early, this is my first week0%
Other: NA0%
Anonymous self-reporting is subject to selection bias and is not clinical evidence. Percentages describe community responses and may not total exactly 100% because of rounding. Snapshot captured 2026-10-16; the source refreshes in the background.
Reported Study Observations & Adverse Events
Research context belongs beside—not above—the safety and evidence boundary.
* Source context: Pep-Pedia research profile ↗. This catalogue uses a research-only summary and does not reproduce protocol or self-use instructions.
Reported observation window*
STAGE 1
Weeks 1–2 · appetite may decrease while mild digestive effects can appear as the body adjusts to triple-receptor activity
STAGE 2
Weeks 2–4 · food cravings and portion sizes may fall, with early weight changes reported in trials
STAGE 3
Weeks 4–8 · appetite control and weight change may become more noticeable; glucose measures may also improve in studied diabetic populations
STAGE 4
Weeks 8–16 · trials report broader weight, energy-expenditure and metabolic changes
STAGE 5
Weeks 16–24 · larger weight changes and improvements in cardiovascular and liver-fat markers have been reported
STAGE 6
Weeks 24–48 · longer studies assess maximum weight response, wider metabolic effects and whether benefits are sustained
Published Evidence & Trial Context
Study type is part of the product information. Laboratory, animal, observational and controlled human findings are not interchangeable.
WEIGHT LOSS
Clinical trials demonstrate 17.5% at 24 weeks and 24.2% at 48 weeks - highest recorded for any obesity medication in development
DIABETES
HbA1c reductions up to 2.16% with 82% of participants achieving target levels below 6.5% - exceeding dual agonist performance
CARDIOVASCULAR
Non-HDL cholesterol reductions up to 26.9%, triglyceride reductions up to 40.6%, and ApoB reductions up to 24.2%
References & citations.＋
Selected studies and source context.
Curated starting points, not a systematic review, comparative ranking or batch-test record. Follow the source for the full methods and results.
| Source | Study model | Measured topic and limitations |
|---|---|---|
| Retatrutide phase 2 study ↗Jastreboff et al. · 2023 · PMID 37366315 | Randomised phase 2 trial · 338 adults · 48 weeks | Measures body-weight change and adverse events in the specified trial population. Read the trial formulation, population, comparator and follow-up; the publication does not certify catalogue material. |
Retatrutide identity and research evidence · Retatrutide vs Tirzepatide compared · Is Retatrutide available in India? · Retatrutide vs Tirzepatide · Research availability in India · Batch COA checklist · Presentation and blend labels · Publisher and source policy
01Retatrutide research profileContent-synthesis source for indications, timelines, safety context and community reportingView source ↗
02PubMed literature for RetatrutideSearch peer-reviewed records for the exact compound nameView source ↗
03ClinicalTrials.gov records for RetatrutideSearch registered studies and their current statusView source ↗
Frequently Asked Questions
What is the Retatrutide price in India?＋
The currently listed INR prices are 10 mg: ₹5,500; 20 mg: ₹8,500; 30 mg: ₹12,000; 40 mg: ₹14,000; Premium Segment: ₹15,000. The prices above are for the labelled research presentations. Confirm availability, delivery charges and the final order total before payment.
Are Retatrutide, Reta and LY3437943 the same research compound?＋
Reta is a common abbreviation for Retatrutide, and LY3437943 is its development code. Match the full material name, labelled presentation and batch identity when comparing product records. A shared name alone does not verify the contents of a vial.
What other names are used for Retatrutide?＋
Reta; LY3437943 are names used in material searches. A receptor-research peptide investigated at GLP-1, GIP and glucagon receptors. Match the full label, form and batch documents; an alias alone does not authenticate a product.
How does Retatrutide compare with Tirzepatide?＋
A receptor-research peptide investigated at GLP-1, GIP and glucagon receptors. A dual GIP/GLP-1 receptor research material. This catalogue presentation is distinct from a finished prescription medicine. Compare identity, component amounts and the actual study model. Shared research topics do not establish equivalent effects.
Can Retatrutide be delivered to Mumbai, Delhi, Bengaluru, Hyderabad, Chennai or Pune?＋
Delivery enquiries are welcome for these cities and other Indian destinations, subject to the actual PIN code. Standard delivery: ₹150, estimated 3–5 days. Express delivery: ₹350, estimated 2–3 days. Cash on delivery adds ₹150. Confirm PIN-code serviceability and the delivery estimate before ordering.
When can I request a return or refund for Retatrutide?＋
Returns and refunds are available for products damaged on arrival or if purity is below 99%. Retain the order reference, packaging and relevant batch records; contact the team to confirm the claim process.
How do I order Retatrutide for research in India?＋
Select the labelled presentation and quantity, review the cart, then send the order enquiry on WhatsApp. Share your Indian PIN code so the team can confirm stock, serviceability, delivery charges and the final INR total before payment. The listed material is for laboratory research only, not for human consumption.
How can I check the Retatrutide batch COA and India delivery?＋
Use the batch COA request link on this page and specify the selected presentation. Ask the team to match available documentation to the current batch and confirm delivery to your Indian PIN code before payment. Compare the report identity, test method and measured result with the material offered.
How much is shipping for Retatrutide in India, and is cash on delivery available?＋
Standard delivery across India costs ₹150 and usually takes 3–5 days. Express delivery costs ₹350 and usually takes 2–3 days. Cash on delivery is available for an extra ₹150. The team confirms serviceability for your PIN code and the final total on WhatsApp before dispatch.
Can I buy Retatrutide in Mumbai, Delhi, Bangalore or Hyderabad?＋
Yes. The Peptide Co. ships from Bengaluru to eligible PIN codes across India, including Mumbai, Delhi NCR, Bengaluru (Bangalore), Hyderabad, Chennai, Pune, Kolkata and Ahmedabad. Share your PIN code on WhatsApp to confirm serviceability and the delivery estimate for your address.
What other names is Retatrutide known by?＋
Retatrutide is also known as Reta, LY3437943. These names describe the same listing on this page; always match the labelled identity and batch documentation rather than relying on a name alone.
How does Retatrutide compare with Tirzepatide?＋
Retatrutide (LY3437943) is an investigational triple GIP, GLP-1 and glucagon receptor agonist; Tirzepatide (LY3298176) is a dual GIP and GLP-1 receptor agonist. Our Retatrutide vs Tirzepatide guide compares identity, receptor targets, research status and label checks. Read the guide at thepeptideco.in/guides/retatrutide-vs-tirzepatide.
Is the Retatrutide listing price on this page current?＋
As of 1 November 2026, this page shows 5 listed presentations for Retatrutide, and prices on the page are read from the live catalogue each time it loads. Current availability is shown with the listed sizes. Your final total is confirmed on WhatsApp.
What exactly is Retatrutide?＋
Retatrutide is classified as synthetic tri-receptor agonist peptide. A 39-amino-acid investigational peptide with a lipid modification studied for prolonged receptor exposure.
What is Retatrutide studied for?＋
Its principal research areas are GIP, GLP-1 and glucagon receptor activity, energy-balance models, metabolic research. These describe experimental topics, not guaranteed outcomes or approved indications.
What form does the product arrive in?＋
10 mg · 20 mg · 30 mg · 40 mg · Premium Segment lyophilized research material in a sealed glass vial. Appearance: White to off-white lyophilized powder. Always compare the received vial with its lot-specific documentation.
How should the unopened material be stored?＋
Store sealed, away from heat, light and moisture; follow the batch documentation for temperature limits.
Is Retatrutide approved for human use?＋
Investigational; not approved for routine human use. This catalogue presentation is restricted to laboratory research material and does not provide dosing, treatment or self-administration guidance.